Understanding Levitra 10mg for Erectile Dysfunction

Tell all your healthcare

• Levitra 10mg is used to address erectile difficulties.
• The medicine improves blood supply to the penis.
• It is not a hormone therapy.
• Avoid use if you have severe heart disease.
• Its effects are enhanced when taken on an empty stomach.
• The medication may influence blood pressure levels.
• Consult your doctor for duration of treatment.
• Inform your healthcare provider about any prior allergies.
• Levitra 10mg can be used in conjunction with certain other ED treatments.
• Keep track of any side effects experienced.
• The medication should be taken only once per dose.

providers that you take LEVITRA.

Ingredient	Description	Quantity per Tablet	Function
Vardenafil	PDE5 inhibitor	10 mg	Helps achieve and maintain erection
Lactose	Filler and binder	-	Ensures tablet integrity
Microcrystalline Cellulose	Diluent	-	Binds ingredients
Magnesium Stearate	Lubricant	-	Prevents ingredients from sticking

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More about Levitra (vardenafil)

In those patients who are stable on alpha-blocker therapy, LEVITRA should be initiated at a dose of 5 mg (2.5 mg when used concomitantly with certain CYP3A4 inhibitors - see Drug Interactions). LEVITRA (vardenafil HCl) is formulated as orange, film-coated round tablets with debossed “BAYER” cross on one side and “10” and “20” on the other side equivalent to 10 mg and 20 mg of vardenafil, respectively. Vardenafil HCl (Levitra) 10mg tablets are supplied in bottles of 2, 4, 6, 12 and 18 tablets per bottle.Vardenafil HCl (Levitra) 20mg tablets are supplied in bottles of 2, 3, 4, 6, 12 and 18 tablets per bottle. Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature]. Bayer HealthCare Pharmaceuticals Inc.Wayne, NJ 07470 LEVITRA is a registered trademark of Bayer Aktiengesellschaft and is used under license by GlaxoSmithKline and Schering Corporation.

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©2008 Bayer HealthCare Pharmaceuticals Inc.Printed in U.S.A. Repackaged by: APHENA PHARMA SOLUTIONS - TN Cookeville, TN 3850620111027AW Read the Patient Information about LEVITRA before you start taking it and again each time you get a refill. You may also find it helpful to share this information with your partner. This leaflet does not take the place of talking with your doctor. You and your doctor should talk about LEVITRA when you start taking it and at regular checkups. for a heart problem, it will

Side Effect	Frequency	Severity	Recommended Action
Headache	Common	Mild to moderate	Take pain relievers, stay hydrated
Flushing	Common	Mild	Cool environment, relax
Nasal Congestion	Common	Mild	Decongestants if needed
Dizziness	Occasionally	Moderate	Avoid driving, sit or lie down

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Product	Dosage	Quantity + Bonus	Price
Levitra Generic	40mg	270 + 10 Pills	561.89€ 535.13€	Buy
Levitra Generic	60mg	180 + 10 Pills	501.43€ 477.55€	Buy
Levitra Generic	40mg	180 + 10 Pills	405.06€ 385.77€	Buy
Levitra Generic	20mg	360 + 10 Pills	458.44€ 436.61€	Buy
Levitra Generic	40mg	120 + 8 Pills	302.37€ 287.97€	Buy
Levitra Generic	20mg	30 + 4 Pills	70.59€ 67.23€	Buy
Levitra Original	20mg	64 + 4 Pills	298.45€ 284.24€	Buy
Levitra Soft Tabs	20mg	10 Pills	52.27€ 49.78€	Buy
Levitra Generic	10mg	270 + 10 Pills	338.09€ 321.99€	Buy
Levitra Generic	20mg	180 + 10 Pills	293.10€ 279.14€	Buy
Levitra Soft Tabs	20mg	30 + 2 Pills	99.17€ 94.45€	Buy

to know when you last took LEVITRA.

Warnings & Precautions

Renal dialysis is not expected to accelerate clearance because vardenafil is highly bound to plasma proteins and is not significantly eliminated in the urine. For most patients, the recommended starting dose of LEVITRA is 10 mg, taken orally approximately 60 minutes before sexual activity. The dose may be increased to a maximum recommended dose of 20 mg or decreased to 5 mg based on efficacy and side effects. The maximum recommended dosing frequency is once per day. LEVITRA can be taken with or levitra professional generic without food.

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Sexual stimulation is required for a response to treatment. Geriatrics: A starting dose of 5 mg LEVITRA should be considered in patients ≥65 years of age (see CLINICAL PHARMACOLOGY, Pharmacokinetics in Special Populations and PRECAUTIONS). Hepatic Impairment: For patients with mild hepatic impairment (Child-Pugh A), no dose adjustment of LEVITRA is required. Vardenafil clearance is reduced in patients with moderate hepatic impairment (Child-Pugh B), and a starting dose of 5 mg LEVITRA is recommended. The maximum dose in patients with moderate hepatic impairment should not exceed 10 mg. LEVITRA is a prescription

• Levitra 10mg tablets come in discreet packaging.
• It is important to complete the prescribed course.
• The medication can improve confidence and sexual performance.
• It is not a cure for erectile dysfunction.
• Levitra 10mg may interact with certain antibiotics and antifungals.
• Avoid driving or operating machinery if side effects occur.
• Discuss all health conditions with your doctor before use.
• Overdose symptoms include severe hypotension.
• Consult your doctor before using if you have a history of stroke.
• Levitra 10mg can be used by men over 18.
• Follow the instructions for optimal effectiveness.

medicine taken by mouth

Is Vardenafil or Viagra More Effective for You?

LEVITRA has not been evaluated in patients with severe hepatic impairment (Child-Pugh C) (see CLINICAL PHARMACOLOGY, Metabolism and ExcretionWARNINGS and PRECAUTIONS). Renal Impairment: For patients with mild (CLcr = 50-80 ml/min), moderate (CLcr = 30-50 ml/min), or severe (CLcr<30 ml/min) renal impairment, no dose adjustment is required. LEVITRA has not been evaluated in patients on renal dialysis (see CLINICAL PHARMACOLOGY, Metabolism and Excretion and PRECAUTIONS). Concomitant Medications: The dosage of LEVITRA may require adjustment in patients receiving potent CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir, indinavir, saquinavir, atazanavir, and clarithromycin as well as in other patients receiving moderate CYP3A4 inhibitors such as erythromycin (see WARNINGS, PRECAUTIONS, Drug Interactions). For ritonavir, a single dose of 2.5 mg LEVITRA should not be exceeded in a 72-hour period.

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For indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, and clarithromycin, a single dose of 2.5 mg LEVITRA should not be exceeded in a 24-hour period. For ketoconazole 200 mg daily, itraconazole 200 mg daily, and erythromycin, a single buy levitra online canadian pharmacy dose of 5 mg LEVITRA should not be exceeded in a 24-hour period. For alpha-blockers, caution is advised when PDE5 inhibitors, including LEVITRA, are used concomitantly with alpha-blockers because of the potential for an additive effect on blood pressure. In some patients, concomitant use of these two drug classes can lower blood pressure significantly (see PRECAUTIONS,Alpha-blockers and Drug Interactions) leading to symptomatic hypotension (e.g., fainting). Concomitant treatment should be initiated only if the patient is stable on his alpha blocker therapy. for the treatment of erectile dysfunction (ED) in men.

Risks and warnings for Vardenafil

No evidence of specific potential for teratogenicity, embryotoxicity or fetotoxicity was observed in rats and rabbits that received vardenafil at up to 18 mg/kg/day during organogenesis. This dose is approximately 100 fold (rat) and 29 fold (rabbit) greater than the AUC values for unbound vardenafil and its major metabolite in humans given the MRHD of 20 mg. In the rat pre-and postnatal development study, the NOAEL (no observed adverse effect level) for maternal toxicity was 8 mg/kg/day. Retarded physical development of pups in the absence of maternal effects was observed following maternal exposure to 1 and 8 mg/kg possibly due to vasodilatation and/or secretion of the drug into milk. The number of living pups born to rats exposed pre- and postnatally was reduced at 60 mg/kg/day.

At what dose is Levitra typically prescribed?

Based on the results of the pre- and postnatal study, the developmental NOAEL is less than 1 mg/kg/day. Based on plasma exposures in the rat developmental toxicity study, 1 mg/kg/day in the pregnant rat is estimated to produce total AUC values for unbound vardenafil and its major metabolite comparable to the human AUC at the MRHD of 20 mg. There are no adequate and well-controlled trials of vardenafil in pregnant women. Elderly males age 65 years and older have higher vardenafil plasma concentrations than younger males (18 – 45 years), mean Cmax and AUC were 34% and 52% higher, respectively (see CLINICAL PHARMACOLOGY,Pharmacokinetics in Special Populations, and DOSAGE AND ADMINISTRATION). Phase 3 clinical trials included more than 834 elderly patients, and no differences in safety or effectiveness of LEVITRA 5, 10, or 20 mg were noted when these elderly patients were compared to younger patients. ED is a condition where the

Side Effects

It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors, to the patient’s underlying vascular risk factors or anatomical defects, to a combination of these factors, or to other factors (see PRECAUTIONS, Information for Patients). Visual disturbances including vision loss (temporary or permanent), such as visual field defect, retinal vein occlusion, and reduced levitra for ed visual acuity, have also been reported rarely in post-marketing experience. It is not possible to determine whether these events are related directly to the use of LEVITRA. Seizure, seizure recurrence and transient global amnesia have been reported post-marketing in temporal association with LEVITRA. Cases of sudden decrease or loss of hearing have been reported post-marketing in temporal association with the use of PDE5 inhibitors, including LEVITRA.

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In some cases, medical conditions and other factors were reported that may have also played a role in the otologic adverse events. In many cases, medical follow-up information was limited. It is not possible to determine whether these reported events are related directly to the use of LEVITRA, to the patient’s underlying risk factors for hearing loss, a combination of these factors, or to other factors (see PRECAUTIONS, Information for Patients). The maximum dose of LEVITRA for which human data are available is a single 120 mg dose administered to eight healthy male volunteers. The majority of these subjects experienced reversible back pain/myalgia and/or “abnormal vision.” In cases of overdose, standard supportive measures should be taken as required. penis does not harden and expand

Condition	Precaution	Explanation
Nitrate medication use	Do not use with nitrates	Risk of severe hypotension
Heart problems	Consult cardiologist before use	May exacerbate underlying conditions
Liver impairment	Dose adjustment or avoid use	Reduced drug metabolism
Allergies to components	Check ingredients	Potential allergic reactions

when a man is sexually excited,

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However, due to increased vardenafil concentrations in the elderly, a starting dose of 5 mg LEVITRA should be considered in patients ≥65 years of age. LEVITRA was administered to over 4430 men (mean age 56, range 18-89 years; 81% White, 6% Black, 2% Asian, 2% Hispanic and 9% Other) during controlled and uncontrolled clinical trials worldwide. Over 2200 patients were treated for 6 months or longer, and 880 patients were treated for at least 1 year. In placebo-controlled clinical trials, the discontinuation rate due to adverse events was 3.4% for LEVITRA compared to 1.1% for placebo. When LEVITRA was taken as recommended in placebo-controlled clinical trials, the following adverse events were reported (see Table 5).

How can I refill my Levitra prescription?

Back pain was reported in 2.0% of patients treated with LEVITRA and 1.7% of patients on placebo. Placebo-controlled trials suggested a dose effect in the incidence of some adverse events (headache, flushing, dyspepsia, nausea, rhinitis) over the 5 mg, 10 mg, and 20 mg doses of LEVITRA. The following section identifies additional, less frequent events (<2%) reported during the clinical development of LEVITRA. Excluded from this list are those events that are infrequent and minor, those events that may be commonly observed in the absence of drug therapy, and those events that are not reasonably associated with the drug. Most, but not all, of these patients had underlying anatomic or vascular risk factors for development of NAION, including but not necessarily limited to: low cup to disc ratio (“crowded disc”), age over 50, diabetes, hypertension, coronary artery disease, hyperlipidemia and smoking. or when he cannot keep an erection.

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If you do not understand the information, or have questions, talk with your doctor or pharmacist. WHAT IMPORTANT INFORMATION SHOULD YOU KNOW ABOUT LEVITRA? LEVITRA can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke. use recreational drugs called “poppers” like amyl nitrate and butyl nitrate.

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